Aldehyde group compounds, as well as preparation method and application thereof
2015
The invention relates to the fields of medicinal chemistry and pharmacotherapeutics, in particular to compounds of a general formula (I), whichserve as an enterovirus protease inhibitor. The compounds have remarkable inhibition activity on coronavirus [SRAS (severe acute respiratory syndromes)] main proteinase and can be used for treating related diseases. The invention also relates to a preparation method of the compounds, a medicinal composition of the compounds, and medicinal salt, enantiomeric form and diastereoisomer as well as racemic compounds. (The formula I is as shown in the description).
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