Diarrhetic shellfish poison standard sample as well as preparation method and application thereof

The invention discloses a diarrhetic shellfish poison (DSP) standard sample as well as a preparation method and an application thereof. The method comprises the following steps: shelling fresh shellfish containing DSP masculine, taking out intestinal gland, adding organic solvent, homogenizing, freeze-drying primarily to obtain a coarse sample, grinding and screening the coarse sample to obtain freeze-dried powder, dispersing the freeze-dried powder in organic solvent again, and freeze-drying to obtain the DSP standard sample. The DSP standard sample has better uniformity and stability, can be used for proficiency testing activities in DSP testing projects in laboratories and for qualitative and quantitative detection of DSP, and can also be used for verification of detection methods, calibration of testing instruments and quality control and evaluation of testing results. The invention has the advantages that the raw materials cost is low, the preparation method is simple, and the obtained standard sample is a substantial standard sample, is uniform and stable, is easy to store, and is beneficial to the effective monitoring to shellfish poisons.