Cervical cancer detection by time-resolved spectra of blood components

Fluorescence spectral techniques are very sensitive, and hence they are gaining importance in cancer detection. The biomarkers indicative of cancer could be identified and quantified by spectral or time domain fluorescence spectroscopy. The results of an investigation of time-resolved spectra of cellular compo- nents of blood obtained from cervical cancer patients and normal controls are given. The cancer indicative bio- marker in this paper is porphyrin; it has a fluorescence decay time of 60% more in samples of cancer patients than those of normal controls. Based on such measurements, a randomized set comprising samples from cancer patients and controls (N ¼ 27 in total) could be classified with sensitivity (92%) and specificity (86%).©TheAuthors. Published by SPIE under a Creative Commons Attribution 3.0 Unported License. Distribution or reproduction of this work in whole or in part requires full