Synthesis, Structure and Biological Activity of Zn（II） Complex with Tris（benzimidazol-2-yl-methyl）amine Ligand

A new Zn(Ⅱ) mononuclear complex with tris(benzimidazol-2-yl-methyl)amine (NTB) was synthesized with stoichiometry of [Zn(NTB)NO3]NO3·DIPY·DMF (DIPY : 4,4′-dipyridyl). The complex was characterized by elemental analysis, UV and IR spectra. The crystal structure was determined by using X-ray diffraction analysis. The crystal structure indicates that four N atoms and one O atom coordinate to zinc ion to construct a distorted trigonal-dipyramid configuration. Three nonprotonated N atoms from imidazole groups are in the equatorial plane, one alkylamino N atom and one O atom from NO3^- in the axial directions. The biological activity assay shows that this complex presents certain biological activity by means of pyrogaUol autoxidation and it can be called a model compound of superoxide dismutase (SOD).