One‐Pot Synthesis of 4‐Substituted 1H‐[1,2,3]triazolo[4,5‐c]quinolines Through CuO‐Promoted Tandem Cyclization Reactions of (E)‐3‐(2‐Bromoaryl)‐1‐arylprop‐2‐en‐1‐ones with Sodium Azide

A facile and efficient protocol for the synthesis of 4-substituted-1H-[1,2,3]triazolo[4,5-c]quinolines through a CuO-promoted tandem cyclization reaction has been developed. This method allows for the construction of two heterocyclic rings in a one-pot reaction of readily available (E)-3-(2-bromoaryl)-1-arylprop-2-en-1-ones and sodium azide without the addition of any additive. A series of triazole-fused N-heterocyclic compounds could be prepared in moderate to good yields.