Original articleErythrocyte oxidative stress markers in children with sickle cell diseaseMarcadores de estresse oxidativo em eritrócitos de crianças com doença falciforme

Objective To determine eight parameters of oxidative stress markers in erythrocytes from children with sickle cell disease and compare with the same parameters in erythrocytes from healthy children, since oxidative stress plays an important role in the pathophysiology of sickle cell disease and because this disease is a serious public health problem in many countries.