Serum zinc, copper and selenium inflammatory bowel disease patients relation with metabolic bone disease

Bone metabolism changes in patients with inflammatory bowel disease (IBD) awoke a growing interest in the past few years mostly because of their high prevalence, with estimations around 40 osteoporosis. Contributing factors including inadequate nutrition, corticosteroid, and decreased physical activity elements play an important role in the growth development and maintenance of bones. The aim of our study was to assess the Bone mineral indexes and correlation with bone mineral density healthy Controls of both gender processed for all baseline parameters. Serum Zinc, Copper and Selenium assessed by Atomic Absorption Spectrophotometry. The subjects were evaluated for Bone Mineral Dens Absorptiometry scan and T score was calculated to assess Osteoporosis. Pearson correlation tests were used for statistical analysis Bone Mineral Density than the Controls. Bone Mineral Density values were not different between the subtypes Disease and Ulcerative Colitis. Though Ulcerative Colitis and Crohn's Disease patients had significantly lower Bone Mineral Density than the Controls. Significantly Low Zinc and selenium level was observed in Inflammatory Bowel disease patients however Copper was found significantly high. correlated with Bone Mineral Den develop metabolic bone disease. Along with other nutrients supplement Zinc, Copper and Selenium should be added to Bone metabolism changes in patients with inflammatory bowel disease (IBD) awoke a growing interest in the past few years mostly because of their high prevalence, with estimations around 40 <50% for osteopenia and 5 Contributing factors including inadequate nutrition, corticosteroid, and decreased physical activity elements play an important role in the growth development and maintenance of bones. The aim of our study was to assess Bone mineral indexes and serum Zinc, Copper, Selenium levels in Inflammatory Bowel Disease patients and their correlation with bone mineral density . One hundred newly diagnosed patients of Inflammatory Bowel Disease and 50 gender ranging in age from 19<50 years were included in the study. Fasting blood samples were processed for all baseline parameters. Serum Zinc, Copper and Selenium assessed by Atomic Absorption Spectrophotometry. The subjects were evaluated for Bone Mineral Dens ity (g/cm2 ) using Dual Energy X T score was calculated to assess Osteoporosis. Student's unpaired t Pearson correlation tests were used for statistical analysis . Inflammatory Bowel Disease patients had si Bone Mineral Density than the Controls. Bone Mineral Density values were not different between the subtypes Ulcerative Colitis. Though Ulcerative Colitis and Crohn's Disease patients had significantly lower Bone Mineral Density than the Controls. Significantly Low Zinc and selenium level was observed in Inflammatory Bowel disease patients however Copper was found significantly high. Zinc, Copper and Selenium level was significantly correlated with Bone Mineral Den sity(r=0.24,<0.25,0.22). Patients with Inflammatory Bowel Disease are more prone to develop metabolic bone disease. Along with other nutrients supplement Zinc, Copper and Selenium should be added to prevent bone loss as well as oxidative stress in Inflamma tory Bowel Disease patient. Inflammatory Bowel Disease, Ulcerative Colitis, Crohn's Disease, Osteopenia , Osteoporosis. Bone metabolism changes in patients with inflammatory bowel disease (IBD) awoke a growing interest in the past few 50% for osteopenia and 5 <30% regarding Contributing factors including inadequate nutrition, corticosteroid, and decreased physical activity . Trace elements play an important role in the growth development and maintenance of bones. The aim of our study was to assess in Inflammatory Bowel Disease patients and their One hundred newly diagnosed patients of Inflammatory Bowel Disease and 50 50 years were included in the study. Fasting blood samples were processed for all baseline parameters. Serum Zinc, Copper and Selenium assessed by Atomic Absorption ) using Dual Energy X Inflammatory Bowel Disease patients had si gnificantly lower Bone Mineral Density than the Controls. Bone Mineral Density values were not different between the subtypes Crohn's Ulcerative Colitis. Though Ulcerative Colitis and Crohn's Disease patients had significantly lower Bone Mineral Density than the Controls. Significantly Low Zinc and selenium level was observed in Inflammatory Bowel Zinc, Copper and Selenium level was significantly Patients with Inflammatory Bowel Disease are more prone to develop metabolic bone disease. Along with other nutrients supplement Zinc, Copper and Selenium should be added to Osteoporosis.