Moving foward and beyond the standard through a non-operative management in rectal cancer? Our watch and wait approach experience in Co-Recto.

3561 Background: Controversies exist about the proper management of pts with clinical complete tumor regression after preoperative therapy. A non-operative management (NOM) of selected patients has achieved promising long-term outcomes in some Watch and Wait (W&W) series. Regardless of encouraging results, and in spite of being a readily accepted strategy by patients, reluctance to recommend this strategy as an affordable option still exists in rectal cancer guidelines. Our aim is to evaluate the NOM for pts with clinical complete response discussed in Co-Recto( interdisciplinary and cooperative team for the Management of rectal cancer) Argentina Methods: Pts with resectable rectal cancer (stage I-III) selected for neoadjuvant therapy in Co-Recto between 2008-2014 were retrospectively reviewed to determine pts with clinical complete response(cCR) selected for Non operative management. cCR was defined between digital exam, endoscopic criteria, MRI and CEA. F-up for W&W policy was performed during the first...