Анализ фармакотерапии острого стенозирующего ларинготрахеита у детей с позиции доказательной медицины

A retrospective analysis of 72 case histories of children diagnosed with acute constrictive laryngotracheitis was performed to assess the rationality of pharmacotherapy according to evidence-based medicine. Constricitive laryngotracheitis occurs in children up to three years, the majority of them are hospitalized on the first day of the disease. In the etiology of the disease the dominant role belongs to parainfluenza virus and influenza B. In 83,3 % of patients doctors use the «traditional/ conventional scheme» inhalation therapy and included the introduction of alternate solution of sodium chloride 0,9 %, solution of epinephrine 0,1 % and hydrocortisone suspension. «The traditional scheme» is often accompanied by the introduction of medications (4-16 inhalations per day), while hydrocortisone is not included in modern algorithms of acute constrictive laryngotracheitis therapy. 16,7 % of patients used inhaled glucocorticoid suspension budesonide, which is reliably effective in acute constrictive laryngotracheitis.