RESERCH ON THE INFLUENCE OF APIDIET IN ACRILAMIDE- INDUCED HEPATOPATHY IN WISTAR RATS ON SOME HEPATIC ENZYMES

Summary In the present experiment, we have assessed for the influence induced by apidiet in in acrylamide-induced hepatopathy in rats. The objecti ves of the experimental study were to investigate the following biochemical parameters: a spartate aminotransferase (ASAT), ALT (alanine transaminase), alkaline phosphatase (ALP), and GGT (gamma glutamyl transpeptidase) in the conditions of chronic hepati c toxicity induced by acrylamide. In order to reduce the influence of factors affecting progression of hepatic lesions, we have administrated apidiet products. Toxic hepatopathy w as experimentally induced administrating of acrylamide (water solution, 50mg/ L concentration) by gastric gavaj. Administration of apidiet plus royal jelly in group which received acrylamide proved to be efficient in maintaining the enzymatic parameter s within normal limits. So, administration of apitherapy products in case of su bjects affected by toxicity determined by aliments compound proved efficient.