Conformational Stable Alleno‐Acetylenic Cyclophanes Bearing Chiral Axes

The design and synthesis of chiral cyclophanes containing signaling functional groups as an integral part of the macrocyclic framework offer promising possibilities for chiral sensing, molecular recognition, and chiral supramolecular architectures. Our research group has been involved in the construction and study of chiroptical properties of several allenic meta- and para-cyclophanes bearing anthracene and pyridine rings as spacers. A revision of our results is presented. Chirality 26:563–573, 2014. © 2014 Wiley Periodicals, Inc.