Cognitive impairment performance and TCM syndrome in the vascular mild cognitive impairment patients with metabolic syndrome

2012 
Objective: To investigate the cognitive impairment performance and TCM syndrome in the vascular mild cognitive impairment patients with metabolic syndrome.Methods: The vascular mild cognitive impairment patients were divided into group of patients with metabolic syndrome(54 cases) and group of patients without metabolic syndrome(142 cases).Cognitive function were assessed using MoCA scale.Chinese medical information were collected.Results: Patients with metabolic syndrome had lower MoCA total score,attention and abstraction ability than patients without metabolic syndrome,but no significant difference were shown in the rest of the cognitive function fields.MoCA were correlated with the number of metabolic syndrome components(r=-0.17,P=0.04).Phlegm,blood stasis were the most common TCM syndrome in the metabolic syndrome group,and significantly higher than the group without metabolic syndrome group(P0.01).Yin deficiency and blood deficiency were the most common TCM syndrome in the group without metabolic syndrome.The main location of disease were both in kidney,liver,spleen,heart in both group.Conclusion: Metabolic syndrome increased the risk of mild cognitive impairment.Vascular mild cognitive impairment patients with metabolic syndrome usually had phlegm and blood stasis based on deficiency.
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