Treatment of purulo-necrotic pathology complicated by associated bacterial microflora in the hoof area in cows

The article is devoted to the problem of purulo-necrotic lesions of the distal extremities, including necrobacteriosis, the study of the role of concomitant bacterial microflora in the occurrence of the disease, as well as the development of new, more effective products safe for animals and product quality. The therapeutic efficacy of the drug Ceftiofur-VS was studied as a result of its use in purulo-necrotic pathologies in the hoof area in cattle. Studies on the comparative therapeutic effectiveness of the drug Ceftiofur-VS in necrobacteriosis in cattle, complicated by associations of microorganisms, were conducted in 2019-2020 in the farms of the Irkutsk region. The objects of the study were 74 cows with purulo-necrotic hoof lesions, with a laboratory-confirmed diagnosis of necrobacteriosis, which were divided into two groups: experimental (50 heads) and control (24 heads). It was found that when using the drug Ceftiofur-VS, a positive therapeutic effect occurred in 46 cows and amounted to 92 %. In the animals of the experimental group, signs of healing were noted already on the 4th day after the start of treatment: the inflammatory reaction (edema and hyperemia) and the affected area significantly decreased, fully cleared from the purulo-necrotic substrate. On the 5th day, young granulations appeared, on the 7th-8th day, signs of purulent inflammation were significantly leveled, exudation from wounds stopped, and marginal epidermization was noted. The average area of the wound was on average about 40% of the original one. The recovery time of animals with necrobacteriosis complicated by associations of microorganisms was, on average, 11-12 days.