Genetic polymorphism of 9 STR loci in Korean population of Mudanjiang

Objective To investigate the genetic polymorphism of 9 short tandem repeats(STR) gene loci,namely CSFLPO,TPOX,TH01,D16S539,D7S820,D13S317,F13A01,FESFPS and vwA in Chinese Korean pop.dabon in Mudanjiang area.Methods Amplified fragment length polymorphism(Amp-FLP)method wLq uscd to get the allele frequeney distribution.Results The genotype distributions of the 9 STR loci are conformed to Hardy-Weinberg equilibrium by x2 test analysis. The total accord frequency,the accumulated total discrimination power and the accumulative exeluding probability of paternity were calculated.Conclusion The results snggested that all the 9 gene loci have high power of excluding probability of patemity and individual identification.They can be used in paternity testing and individual identificmion for forensic medicine.The gene frequencies of CSnP0.TP0X and TP01 gene loci have signifieant differences between the Korean population in Mudanjiang area and those in Yanji area,but there is no difference in gene loci 0f D7S820.D17S317 and vWA. Key words: short tandem repeat;  genetic polymorphism;  Korean population