Two consecutive studies using oral UFT-based chemotherapy regimens in elderly patients with advanced colorectal cancer

Background The continuous oral administration of UFT simulates protracted continuous intravenous infusion of fluorouracil, making this oral therapy a possible substitute for intravenous chemotherapy. Currently, 70% of cases of cancer will occur in patients over 65, and the feasibility of oral administration makes UFT a good drug for the elderly. The main objective of our trials was to evaluate the tolerance and benefits of this oral treatment in elderly patients with advanced colorectal cancer (CRC).