Adenylosuccinate lyase hydroxylation contributes to triple negative breast cancer via the activation of cMYC

Giada Zurlo,Qing Zhang

Adenylosuccinate lyase hydroxylation contributes to triple negative breast cancer via the activation of cMYC

2020

Giada Zurlo
Qing Zhang

ABSTRACTHydroxylation is a post-translational modification affecting protein stability, activity or interactome. We identified adenylosuccinate lyase (ADSL) as a novel hydroxylation substrate in tr...

Keywords:

Cancer research
Chemistry
Hydroxylation
Triple-negative breast cancer
Adenylosuccinate lyase
Biochemistry
Adenosine
Substrate (chemistry)
protein stability
Interactome

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