Perforated Peptic Ulcer Disease: Factors Predicting The Mortality And Morbidity In A Tertiary Care Centre In Southern India.

Background: Perforation is the most common complication of peptic ulcer disease. In spite of modern progress in the management, it is still a life-threatening catastrophe. Perforation may occur in a patient with previous history of ulcer disease or it may happen without any prior symptoms.Methods: This study comprises a retrospective analysis of all patients diagnosed of perforated peptic ulcer disease at SNMC AND HSK HOSPITAL, Bagalkot, INDIA, during the years 2006 to 2011. Clinical data were recorded and analyzed.Results: Out of 180 patients, 136 were males and 44 were females. The age of the patients varied from 18 to 86 years. Gastric perforation was seen in only 17 patients out of 180 and the rest of the patients had duodenal perforation. All the patients underwent surgical treatment of simple closure with omental patch and peritoneal lavage. Postoperative complications occurred in 47 [26.1%] patients and there were 24 deaths [13.3%].Conclusion: We conclude that morbidity and mortality are associated with age of the patients, haemodynamic instability, operative delay, site of the ulcer, peritoneal contamination and quality of postoperative care.