Different doses of bupivacaine in combined spinal-epidural anesthesia in aged people with urinary system disease clinical research

OBJECTIVE To investigate the different doses of bupivacaine in combined spinal-epidural anesthesia in elderly patients with urinary system disease.METHODS 56 cases with urinary surgical operation were collected from July 2009-July 2010,and they were randomly divided into small dose(3G/L)bupivacaine group and high dose(5g/L)bupivacaine group.28 cases were in each group.Implementation of bupivacaine in combined spinal-epidural anesthesia was used for them.We compared the two groups of anaesthetic effect(anesthesia block scope,duration of analgesia,motor nerve recovery time)and mean arterial pressure.RESULTS Small dose group block anesthesia was ranged from 7.51+1.26 section,and the small dose group was significantly less than that of the large dose group(9.22 ± 1.54 section)(P﹤0.05);In small dose group,the duration of analgesia was ranged for(139.72 ± 12.65)min,and was(141.93 ± 11.82)min in the large dose group(P﹥0.05);In the small dose of group,the motor nerve recovery time was 74.89+ 13.32min,which was significantly earlier than the large dose group(121.94 ± 12.87)min(P﹤0.05).Before the two groups,mean arterial pressure of the anesthesia had no significant difference(P﹥0.05);5min,15min and 30min after anesthesia with small dose group showed no significant change(P﹥0.05).The mean arterial pressure of high dose group 5min,15min and 30 min significantly decreased(P﹤0.05),and there were significant difference in the small and high dose groups(P﹤0.05).CONCLUSION 3G/L bupivacaine in combined spinal-epidural anesthesia applied in senile disease of urinary system in the operation had good effect of anesthesia.The effect on blood pressure of motor nerve recovery is faster,smaller,and it may be said of such patients ideal anesthetic means.