Reduzierung des Konservierungsschaden der Rattenleber durch Modifikationen der HTK-Lösung

Optimal organ preservation remains a continuous problem in liver transplantation and preservation quality is a main factor influencing graft failure. Based on new insights in pathophysiologic mechanisms modifications of the HTK solution have been made to reduce cold-storage injury (histidine was partially substituted by N-acetyl-histidine, chloride was replaced by aspartate and lactobionate and glycine, alanine and arginine were supplemented).