Synthesis and Antiviral Evaluation of New N‐acylhydrazones Containing Glycine Residue

N-acylhydrazones containing glycine residue 3a–j and 8a–h were synthesized as HIV-1 capsid protein assembly inhibitors. The structures of the novel N-acylhydrazone derivatives were characterized using different spectroscopic methods. Antiviral activity demonstrated that compound 8c bearing 4-methylphenyl moiety was the most active with low cytotoxicity.