Temperature dependence of the ionization constants and pH values of aqueous solutions of 3-hydroxypyridine

1. The influence of the temperature on the pH of solutions of 3-hydroxypyridine has been studied in the pH range of 2.0–10.0 and the temperature interval of 26–90°C, and equations have been derived describing the dependence of the ionization constants on the temperature. 2. The rate constants of exchange characterizing the contribution of the neutral and ionic forms of 3-hydroxypyridine in the deuterium exchange reactions of the H2, H6, and H4 protons have been obtained with corrections for the temperature changes in the pH values of the solutions.