Robust graft survival and normalized dopaminergic innervation do not obligate recovery in a Parkinson disease patient.
2017
Objective
The main goal of dopamine cell replacement therapy in Parkinson disease (PD) is to provide clinical benefit mediated by graft survival with nigrostriatal reinnervation. We report a dichotomy between graft structure and clinical function in a patient dying 16 years following fetal nigral grafting.
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