Preparation method of tedizolid and intermediate of tedizolid
2015
The invention relates to a preparation method of tedizolid. According to the preparation method, a novel intermediate compound I is adopted to prepare tedizolid, and the specific synthesis route is as shown in the specification, wherein R is selected from H, formulae as shown in the specification, benzyl or substituted benzyl; a substituent group is selected from halogen, nitryl, a group consisting of C1-6 alkyl and C1-6 alkoxy; R1 is optionally substituted C1-6 alkyl; X is a leaving group; the leaving group comprises chlorine, bromine, iodine, sulfonyloxy such as trifluoro-methylsulfonyloxy, mesyloxy and phenylsulfonyl, or phenylsulfonyl which is substituted by one or more substituent groups; the substituent groups can be selected from halogen, C1-6 alkyl and groups consisting of C1-6 alkoxy.
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
0
References
0
Citations
NaN
KQI