Successful treatment of AIDS-related cryptosporidial sclerosing cholangitis

Objective: Cryptosporidium is a well recognized cause of AIDS-related sclerosing cholangitis for which no efficaceous therapy exists at present. We evaluated the efficiency of the combination of paromomycin and letrazuril in the treatment of this condition. Case report: We report a case of cryptosporidial cholangitis in a patient with AIDS who responded to treatment with intravenous paromomycin followed by oral letrazuril as maintenance therapy. Conclusion: The combination of paromomycin and letrazuril should be considered in the treatment of AIDS-related sclerosing cholangitis