Association between tumor necrosis factor-α promoter −308 A/G polymorphism and susceptibility to sepsis and sepsis mortality: A systematic review and meta-analysis

Objective:The tumor necrosis factor (TNF)-α promoter −308 A/G polymorphism has been reported to be associated with sepsis with inconsistent results. We conducted a systematic review and meta-analysis to determine whether the TNF-α −308 A/G polymorphism TNF2 (G/A or A/A) confers susceptibility to sep