Function of the Hypertrophic Right and Left Ventricles in Experimental Conditions

The heart responds to a chronically increased load by an important adaptive mechanism, myocardial hypertrophy. The condition involves comprehensive and dynamic transformation of the heart at the level of organ, cells, and subcellular structures. However, the adaptive process, in addition to its positive aspects, includes adverse changes that may be associated with functional impairment and the development of cardiac failure.