Abstract WP31: Mechanical Thrombectomy Performs Similarly in Real-World Clinical Practise as in Randomized Trials: Nationwide Study From the Czech Republic

Background: In randomized clinical trials (RCTs) mechanical thrombectomy (MT) was proved to be a highly effective and safe treatment in acute ischemic stroke. Its efficacy and safety in routine practice needs to be documented. Methods: Available nationwide 2016 data for the Czech Republic (CR) from SITS-TBY registry of patients with terminal internal carotid artery (ICA) and/or middle cerebral artery (MCA) occlusion were compared with data from HERMES meta-analysis. Categorical variables were compared by Pearson′s Chi-squared test, ordinal/continuous variables by Mann-Whitney test. Results: Fourteen/15 comprehensive stroke centres reported data to SITS-TBY. From 1,053 MTs performed in the CR, 845 (80%) patients were reported to SITS-TBY. From these patients, 605 (72%) patients were involved in analyses (available outcome data in Tab.). CR and HERMES patients were comparable in: age, sex, baseline NIHSS. Occlusion locations were as follows (CR vs. HERMES): ICA 22% vs. 21% (p=0.16), M1 MCA 62% vs. 69% (p=0....