Primary Squamous Cell Carcinoma of the Caecum: Case Report and Update

First described in 1919, primary squamous cell carcinoma (SCC) of the large bowel is an extremely rare colonic malignancy that appears to arise preferentially within the caecum. The underlying aetiology remains unclear, although it may involve chronic inflammation leading to glandular-squamous metaplasia. Here we present the case of a young male patient who presented following an episode of collapse secondary to an acute-gastrointestinal bleed, who was subsequently found to have metastatic SCC of the caecum. Whereas the survival from colorectal adenocarcinoma has improved dramatically over the previous 100-years, prognosis from caecal SCC remains very poor.