A novel scoring system to predict survival in patients with advanced pancreatic adenocarcinoma: The Memorial Sloan Kettering Cancer Center (MSKCC) Prognostic Score (MPS).

4105Background: A major limitation of several common prognostic tools, e.g. the Eastern Cooperative Oncology Group (ECOG), Karnofsky, and Palliative Performance Scales, is a reliance on subjective clinical assessment. An objective tool, the Glasgow Prognostic Score (GPS) derived from C-reactive Protein (CRP) and albumin levels, has been validated in patients with operable and inoperable malignancies but has the disadvantage that CRP is not routinely measured in the United States. We examined if the Neutrophil-Lymphocyte Ratios (NLR) (Ahn, H.K., et al., Neutrophil-Lymphocyte Ratio Predicts Survival in Terminal Cancer Patients. J Palliat Med, 2016) could be substituted for CRP in the GPS to predict survival in patients with advanced pancreatic adenocarcinoma. Methods: A retrospective review chart identified patients at MSKCC with pathology-confirmed stage IV pancreatic adenocarcinoma diagnosed between 2011 to 2014. Pre-treatment absolute neutrophil count, absolute lymphocyte count, and albumin were extracte...