STRUCTURE OF CHEMICAL COMPOUNDS, METHODS OF ANALYSIS AND PROCESS CONTROL HPLC-BASED QUALITY CONTROL OF CYTARABINE PREPARATIONS

-arabinofuranosylcytosine, Ara-C) and uracilarabinoside (Ara-U, a product of the hydrolytic deamination of Ara-C), as well other related compounds(cytidine, cyclocytidine, uridine), in aqueous solutions has been developed. The proposed method is charac-terized by good reproducibility and is capable of quantitatively determining all compounds simultaneouslypresent in solution.