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Synthesis of β-TrifluoromethylatedEnones: An Unexpected Reactivity of Trifluoromethylated WeinrebEnamides towards Organolithium Species
2009
β-Trifluoromethylated enones can be synthesized in four steps from ethyl trifluoroacetoacetate. The key intermediate is a weinreb p-trifluoromethylated enamide.
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