Синтез и антимикобактериальная активность триазеновых производных N-арилкарбаматов
2005
By condensation of equimolar amounts of alkyl-N-(4-nitrosophenyl)carbamates with substituted hydrazines in ethanol were obtained respective triazene derivatives of N-arylcarbamates. It was shown that the chemical modification of isonicotinic hydrazide to respective triazene derivatives of N-arylcarbamates did not result in essential decrease of antimicobacteritic activity ( in vitro ) against Micobacterium tuberculosis and Micobacterium lufu in comparison with isoniazid and dapsone.
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