Cohort Profile: Multimorbidity in Children and Youth Across the Life-course (MY LIFE) Study

Objective: This manuscript serves to provide an overview of the methods of the Multimorbidity in Children and Youth across the Life-course (MY LIFE) study, profile sample characteristics of the cohort, and provide baseline estimates of multimorbidity to foster collaboration with clinical and research colleagues across Canada Method: MY LIFE is comprised of 263 children (2-16 years) with a physical illness recruited from McMaster Children's Hospital, their primary caregiving parent, and their closest-aged sibling Participants are followed with data collection at recruitment, 6, 12, and 24 months which includes structured interviews, self-reported measures, and biological samples and occur in a private research office or at participants' homes Post-COVID-19, data collection transitioned to mail and telephone surveys Results: At recruitment, children were 9 4 (4 2) years of age and 52 7% were male The mean duration of their physical illness was 4 5 (4 1) years;25% represent incident cases (duration <1 year) Most (69 7%) had healthy body weight and intelligence in the average range (73 5%) Overall, 38 2% of children screened positive for =1 mental illness according to parent report (24 8% screened positive based on child self-report) Compared to 2016 Census data, the MY LIFE cohort overrepresents families of higher socioeconomic status Conclusions: Multimorbidity is common among children and these baseline data will serve to measure relative changes in the mental health of children with physical illness over time MY LIFE will provide new information for understanding multimorbidity among children, though underrepresentation of lower socioeconomic families may have implications for the generalizability of findings (English) [ABSTRACT FROM AUTHOR] Objectif: Le present manuscrit sert a presenter un apercu des methodes de l'etude sur la multimorbidite chez les enfants et les jeunes tout au long de la vie (MA VIE), a esquisser des caracteristiques d'echantillon de la cohorte et a fournir des estimations de base de la multimorbidite pour faciliter la collaboration avec les collegues cliniques et chercheurs du Canada Methode: MA VIE comprend 263 enfants (de 2 a 16 ans) souffrant d'une maladie physique recrutes a l'hopital pour enfants de McMaster, leur principal parent aidant, et leurs freres et soeurs les plus rapproches en âge Les participants sont suivis par une collecte de donnees lors du recrutement, a 6, 12, et 24 mois, ce qui comporte des entrevues structurees, des mesures auto-declarees, et des echantillons biologiques qui sont preleves dans un bureau prive de la recherche ou au domicile de participants La collecte de donnees post-COVID-19 a effectue une transition par la poste et les sondages par telephone Resultats: Lors du recrutement, les enfants avaient 9,4 (4,2) ans et 52,7 % etaient de sexe masculin La duree moyenne de leur maladie physique etait de 4,5 (4,1) ans;25 % representaient des cas incidents (duree < 1 an) La plupart (69,7 %) avait un poids corporel sain et une intelligence dans la moyenne (73,5 %) En general, 38,2 % des enfants avaient un depistage positif pour = 1 maladie mentale selon le rapport des parents (24,8 % avaient un depistage positif selon l'auto-declaration des enfants) Comparativement aux donnees du recensement de 2016, la cohorte MA VIE surrepresente les familles de statut socio-economique plus eleve Conclusions: La multimorbidite est commune chez les enfants et ces donnees de depart serviront a mesurer les changements relatifs de la sante mentale des enfants souffrant de maladie physique avec le temps MA VIE fournira de nouvelles informations pour comprendre la multimorbidite chez les enfants, quoique la sous-representation des familles au faible statut socio-economique puisse avoir des implications pour la generalisabilite des resultats (French) [ABSTRACT FROM AUTHOR] Copyright of Journal of the Canadian Academy of Child & Adolescent Psychiatry is the property of Canadian Academy of Child & Adolescent Psychiatry and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission However, users may print, download, or email articles for individual use This abstract may be abridged No warranty is given about the accuracy of the copy Users should refer to the original published version of the material for the full abstract (Copyright applies to all Abstracts )