Selective targeting of bone and cartilage with multivalent dendritic polyanions

Synthesis of Dye-Labeled Polyanions In previous studies native and demineralized ovine bone was used to analyze the affinity of polyanions derived from dendritic polyglycerol (dPG) towa Selective Targeting of Bone and Cartilage with Multivalent Dendritic Polyanions Sabine Reimann1, Dominic Groger1, Ngee Han Lim2, Kai Licha3, Pia Welker Peter Fratzl5, Rainer Haag 1Institute of Chemistry and Biochemistry, Freie Universitat Berlin, Takustr. 3, 14195 Berlin, of Medicine, Imperial College London, 1 Aspenlea Rd, London W6 8LH, UK 3Zentralinstitut Universitatsmedizin Berlin, CBF, Hindenburgdamm 30, 12203 Berlin, Germany 4Charite-Universitatsmedizin und Wiederherstellungschirurgie Garystr. 5, D-14195, Berlin, Germany 5Max Planck Institute Potsdam, Germany.