A Novel Curcumin-Diethyl Fumarate Hybrid as Dualistic GSK-3β Inhibitor/Nrf2 Inducer for the Treatment of Parkinson's Disease.

Rita Maria Concetta Di Martino,Letizia Pruccoli,Alessandra Bisi,Silvia Gobbi,Angela Rampa,Ana Martinez,Concepción Pérez,Loreto Martínez-González,Maria Paglione,Elia Di Schiavi,Francesca Seghetti,Andrea Tarozzi,Federica Belluti

A Novel Curcumin-Diethyl Fumarate Hybrid as Dualistic GSK-3β Inhibitor/Nrf2 Inducer for the Treatment of Parkinson's Disease.

2020

Rita Maria Concetta Di Martino
Letizia Pruccoli
Alessandra Bisi
Silvia Gobbi
Angela Rampa
Ana Martinez
Concepción Pérez
Loreto Martínez-González
Maria Paglione
Elia Di Schiavi
Francesca Seghetti
Andrea Tarozzi
Federica Belluti

Common co-pathogenic factors, including oxidative stress and neuroinflammation, are found to play a vital role in the development of neurodegenerative disorders, including Alzheimer’s disease (AD) ...

Keywords:

Pharmacology
Inducer
Curcumin
Parkinson's disease
Oxidative stress
Chemistry
Diethyl fumarate
Neuroinflammation
Disease

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