Prevalence of Multi-Drug Resistant Bacteria Associated with Diarrhoea among Infants in Ado Ekiti, Nigeria.

Bacteriological investigations were carried out on faecal samples of 76 patients, less than one year of age, attending paediatric clinic of Ekiti State University Teaching Hospital Ado Ekiti and two Primary Health Centres in Ado Ekiti, on diarrhoea related illnesses; in the year 2013. The bacteria isolated were Proteus vulgaris , Pseudomonas aeruginosa , Escherichia coli , Corynebacterium accolens , Morganella morgani , Aeromonas popoffii , Citrobacter freundii , Leteococcus sanguinis , Branchiibius cervicis , Aeromonas bestiarum , Vibrio minicus , Aeromonas caviae , Proteus mirabilis , Serratia marcescens , Enterobacter aerogenes , Leminorella grimontii , Citrobacter youngae , Bacillus cereus , Citrobacter koseri , Enterobacter intermedius , Yersinia enterocolitica , Providencia stuartii , Pantoea agglomerans , Vibrio fluvalis , Vibrio natiensis , Salmonella enterica , Citrobacter sedlakii , Klebsiella variicola . The bacterial isolates showed high resistance to many of the antibiotics tested. High prevalence of multidrug resistant bacteria was recorded. The Gram positive bacteria showed high resistance to most of the antibiotics used. The Gram negative bacterial isolates were 100% susceptible to Levofloxacin and ofloxacin, with a 100% resistant to amoxicillin and varied resistance to other antibiotics. In general, for the gram negative bacterial isolates, the penicillins are the most ineffective group of antibiotics, while the quinolones are the most efficacious. Resistance to high concentrations of penicillins was obtained. The prevalence of multidrug reported in the study could lead to its failure of antibiotic therapy and prolong hospitalization of diarrhoeic infants. Key words : Bacteria, diarrhoea, infant, multi drug resistance