Abstract 12385: TBX5-Based Lineage Tracing Identifies a Propensity for Left Ventricular Cardiomyocyte Differentiation of Human Induced Pluripotent Stem Cells Using Biphasic Modulation of WNT Signaling

Francisco X. Galdos,Soah Lee,William R. Goodyer,Sharon L. Paige,Carissa Lee,Sidra Xu,Gabriela V Escobar,Rasmus O. Bak,Matthew H. Porteus,Sean M. Wu

Abstract 12385: TBX5-Based Lineage Tracing Identifies a Propensity for Left Ventricular Cardiomyocyte Differentiation of Human Induced Pluripotent Stem Cells Using Biphasic Modulation of WNT Signaling

2021

Francisco X. Galdos
Soah Lee
William R. Goodyer
Sharon L. Paige
Carissa Lee
Sidra Xu
Gabriela V Escobar
Rasmus O. Bak
Matthew H. Porteus
Sean M. Wu

Introduction: Patient-derived induced pluripotent stem cells (iPSCs) present an exciting avenue for the modeling of adult and congenital heart diseases. While hiPSC cardiac differentiations generat...

Keywords:

Wnt signaling pathway
Human Induced Pluripotent Stem Cells
Induced pluripotent stem cell
Cardiomyocyte differentiation
stem cell biology
lineage tracing
Medicine
Cell biology

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations