Neuroendocrine Disorders in Children

Section 1: The GH-IGF1 axis and the brain 1. Normal hypothalamo-pituitary function and the neuroendocrine regulation of growth, 2. Disorders of the GH-IGF1 axis leading to growth failure, 3. The effect of growth hormone on the brain 4. Impact of disorders of the GH-IGF1 axis on neurological functioning in childhood 5. Neuroencocrine Disorders of salt and water balance Section 2: The thyroid axis and the brain 6. The hypothalamic-pituitary-thyroid axis: anatomy and physiology 7. Disorders of the hypothalamo-pituitary-thyroid 8. Impact of Thyroid Disorders on Neurological Function Section 3: Regulation of appetite and weight 9. The role of the hypothalamus in normal weight regulation 10. Genetic childhood obesity syndromes 11. Treatment of Obesity Section 4: Effects of treatment of cancer on the neuroendocrine system 12. Late effects of cancer and its treatments on the neuroendocrine system, 13. Craniopharyngioma Section 5: Adrenal disorders and the brain 15. The hypothalamo-pituitary-adrenal axis and its regulation 16. The effect of stress on the hypothalamic-pituitary-adrenal axis: an update 17. Adrenoleukodystrophy- neurological aspects 18. Cushing disease: diagnosis and management Section 6: Neuroendocrinology and the reproductive axis 19. The hypothalamic-pituitary-gonadal axis 20. Disorders of gonadotrophin secretion Hypogonadotrophic hypogonadism 21 Precocious puberty 22. Psychological and behavioural consequences of gonadal hormone abnormality during early development Section 7 Neurological complications of diabetes mellitus 23. Diabetes and the developing brain 24. The Central actions of insulin