Overexpression of type 1 angiotensin II receptors impairs excitation-contraction coupling in the mouse heart

Katy Rivard,Scott A. Grandy,Annie Douillette,Pierre Paradis,Mona Nemer,Bruce G. Allen,Céline Fiset

Overexpression of type 1 angiotensin II receptors impairs excitation-contraction coupling in the mouse heart

2011

Katy Rivard
Scott A. Grandy
Annie Douillette
Pierre Paradis
Mona Nemer
Bruce G. Allen
Céline Fiset

Transgenic mice that overexpress human type 1 angiotensin II receptor (AT1R) in the heart develop cardiac hypertrophy. Previously, we have shown that in 6-mo AT1R mice, which exhibit significant ca...

Keywords:

Calcium
Cardiac cycle
Ventricle
Mouse Heart
Angiotensin receptor
Genetically modified mouse
Diabetes mellitus
Biology
Endocrinology
Internal medicine
Muscle hypertrophy
Angiotensin II
Excitation–contraction coupling

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