Ehlers-Danlos Syndrome Type VIII-A Case Report

Ehlers-Danlos syndrome (EDS) is a genetically heterogeneous connective tissue disorder which is comprised of more than 10 phenotypes including EDS-Ⅷ (periodontitis type), which is characterized by chronically inflamed pretibial lesions and severe periodontitis. We describe a 26-year-old female with a long-standing history of abnormal scarring tissues, presenting with pretibial waxy violaceous plaques for more than 20 years. Premature loss of permanent teeth is also noted. Combining the clinical manifestations and laboratory examinations, we conclude this is a rare case of Ehlers-Danlos syndrome type Ⅷ. There is no specific treatment currently.