Von Hippel-Lindau Syndrome Combined with Bilateral Renal Carcinoma:A Case Report and Review of the Literature

Von Hippel-Lindau(VHL) disease is an autosomal dominant multicancer syndrome,which can involve multiple organs and have various clinical manifestations,such as central nervous system hemangioblastoma,internal organ cancer and internal organ multiple cysts.This paper,reported a case of von Hippel-Lindau syndrome combined with bilateral renal carcinoma and reviewed the literature about the clinical features,diagnostic methods and management of VHL disease.