Study on P-CNB Induced SOD and CAT Activities in Brocarded Carp Liver

The acute toxicity of p-CNB (p-Chloronitrobenzene) to Brocarded Carp and 2 kinds of antioxidant activities in liver of fish were investigated. The acute toxicity test showed that 24 h, 48 h, 72 h, 96 h value of median lethal concentration (LC 50 ) at 20-22degC were 30.98, 24.89, 23.9 and 19.93 mg/L, respectively. Fish was exposed to different concentrations (1/6LC 50 , 1/4LC 50 , 1/3LC 50 , 1/2LC 50 ) and killed at 3, 7, 14, 21 and 28 day after exposure. The activities of Superoxide dismutase (SOD) and Catalase (CAT) in liver tissue were analyzed. The results indicated the activities of SOD and CAT were induced from the third day in all treatment groups at post-exposures, they were higher than those of the control group ( p CAT.