Effects of the selective endothelin A (ET(A)) receptor antagonist Clazosentan on cerebral perfusion and cerebral oxygenation following severe subarachnoid hemorrhage - preliminary results from a randomized clinical series.

Martin Barth,Hans Holger Capelle,E. Münch,Claudius Thomé,Fritz Fiedler,Peter Schmiedek,Peter Vajkoczy

Effects of the selective endothelin A (ET(A)) receptor antagonist Clazosentan on cerebral perfusion and cerebral oxygenation following severe subarachnoid hemorrhage - preliminary results from a randomized clinical series.

2007

Martin Barth
Hans Holger Capelle
E. Münch
Claudius Thomé
Fritz Fiedler
Peter Schmiedek
Peter Vajkoczy

Objective. To study the effects of clazosentan, a new selective endothelin receptor subtype A antagonist, on cerebral perfusion and cerebral oxygenation following severe aneurysmal subarachnoid haemorrhage (aSAH).

Keywords:

Antagonist
Anesthesia
Receptor antagonist
Cerebral perfusion pressure
Surgery
Stroke
Cerebral blood flow
Subarachnoid hemorrhage
Endothelin receptor
Medicine
Vasospasm
Neurology

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