GERD and Eosinophilic Esophagitis

GERD and EoE cause chronic esophageal inflammation sharing some common characteristics. Distinction between them requires detailed evaluation of clinical, endoscopic, and histologic features. The interplay between these pathologies is complex and still under active investigation. GERD and EoE may also coexist. The current diagnostic tests may not provide clear-cut differences in diagnosis. Combined clinical, endoscopic, and histologic data may provide the best diagnostic criteria to identify the exact diagnosis and take appropriate therapeutic options.