Preliminary data on antitumor activity of extracorporeal subtraction of soluble TNFRs to unleash the activity of endogenous TNFα combined with chemotherapy in treatment-refractory, advanced, triple-negative breast cancer patients.

Piotr J. Wysocki,Adam Ostrowski,Robert Segal,Paweł Potocki,Kamil Konopka,Lukasz Kwinta,Lawrence B Florin,Stephen M. Prince

Preliminary data on antitumor activity of extracorporeal subtraction of soluble TNFRs to unleash the activity of endogenous TNFα combined with chemotherapy in treatment-refractory, advanced, triple-negative breast cancer patients.

2021

Piotr J. Wysocki
Adam Ostrowski
Robert Segal
Paweł Potocki
Kamil Konopka
Lukasz Kwinta
Lawrence B Florin
Stephen M. Prince

e13052Background: Tumor necrosis factor-alpha (TNFα) is a pleiotropic cytokine, with known antitumor activity, produced mainly by activated immune cells. Cancer cells neutralize TNFα by shedding so...

Keywords:

Medicine
Endogeny
Chemotherapy
Cytokine
Cancer research
Extracorporeal
Triple-negative breast cancer
Cancer cell
Tumor necrosis factor alpha
Immune system

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