Purification of flavonoids from glycyrrhiza by MAR mixed-bed

Purpose The purpose of this paper is to separate and purify flavonoids from glycyrrhiza by macroporous adsorption resin (MAR) mixed-bed technology. Design/methodology/approach The adsorption performance of MAR and MAR mixed bed for flavonoids was studied using ultraviolet-visible spectrophotometry. Findings The research shows that the MAR mixed bed of LZ-50+LZ-59 with a mass ratio of LZ-50:LZ-59(m:m) = 1:1 was the optimized combination with the optimal conditions of adsorption (pH = 6, T = 45°C) and desorption (liquid ratio R = 70%, T = 50°C, pH = 8) obtained, relatively. Originality/value This paper provides a novel way to separate flavonoids from glycyrrhiza. Under the optimal conditions, the adsorption rate (F) of MAR mixed-bed LZ-50+LZ-59 to the flavonoids was 62.5 per cent/g, the desorption rate (D) was 89.23 per cent and the purity was achieved at 80 per cent.