PRIMA-1 MET -induced neuroblastoma cell death is modulated by p53 and mycn through glutathione level
2019
Background
Neuroblastoma is the most common extracranial solid tumor in children. This cancer has a low frequency of TP53 mutations and its downstream pathway is usually intact. This study assessed the efficacy of the p53 activator, PRIMA-1MET, in inducing neuroblastoma cell death.
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