Features of surgical treatment of cerebellar astrocytomas in children of the first years of life
2016
Introduction: Astrocytomas make up to 30-50% of all brain tumors in children and remains one of the actual problems of pediatric neurosurgery. Objective: To conduct a retrospective analysis of the treatment of cerebellar astrocytomas in children of early age during 30 years, to identify the factors determining the prognosis of the disease. Materials and methods: Results of treatment of 83 children of early age, operated for astrocytomas of cerebellum in the Pediatric Department in 1980-2009 years were analyzed. Male patients were 48 (57.8%), female — 35 (41.2%). Benign astrocytomas are diagnosed in 67 (80.7%) cases and malignant in 16 (19.3%). Astrocytoma of the cerebellum in 43 (51.8%) children contained a cystic component. Postoperative mortality over a 30-year period was 15.8%. Catamnesis was analyzed in 65 patients in terms in average 6.1 years. The evaluation of quality of life was based on a scale Yu.A. Orlov (2007). Results: The total removing of the tumor was done in 61.9% of patients, subtotal in 26.3%, partial in 11.8%, biopsies of tumours in 1.2%. Shunt surgery complement the removing of tumors in 40.8% cases. Postoperative mortality rate decreased from 18.2% in 1980-1989. to 6.7% in 2000-2009. In 1980-1989 years total removal was in 35.4%, in 2000-2009 in 66.7%. Survival at 1 year after operation was in 93.8%, 2 years – in 86.1%, 5 years – in 67.7% of cases. The good quality of life was noted in 21 (32.3%) of the children, satisfactory in 35 (53.8%), poor in 7 (10.8%) and the vegetative state in 2 (3.1%) children. Conclusions: The amount of removal of the tumor, the degree of malignancy, presence of cystic components affect the quality and duration of life of children of early age with cerebellar astrocytomas.
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
4
References
0
Citations
NaN
KQI