57. Correlation between electroencephalographic findings and the degree of activity in patients with neuropsychiatric involvement studied at the National Institute of Medical Sciences and Nutrition Salvador Zubiran

Objective Determine if there is a correlation between Systemic Lupus Erythematosus Disease Activity Index (SLEDAI) and the severity of electroencephalographic findings categorized according to the classification of abnormality used by Cleveland Clinic Foundation. Material and methods A descriptive, cross-sectional and retrospective study in patients with diagnosis of SLE and neuropsychiatric involvement, sent to EEG studies between January 2010 and May 2015 with adequate studies to complete SLEDAI. Results Of 94 patients referred with a diagnosis of SLE, 38 met the inclusion criteria, recording 40 episodes of evaluation. Ninety-two percent were women; the mean age was 35 years. After the nonparametric Spearman correlation analysis we found a weak correlation ( r  = 0.38) nonetheless significant ( p  = 0.05) between the SLEDAI index and the degree of abnormality in EEG. Nonparametric tests of the differences between groups, showed that patients who had seizures, previously not diagnosed as epileptic, tended to have higher disease activity (2.28 1.2) vs: those who did not have seizures (1.65 1.19) with p  = 0.06. Conclusions Patients with higher levels of SLE activity, tend to have higher rate of EEG abnormalities.