Oxygen-promoted Suzuki–Miyaura reaction of aryl fluorosulfates and potassium aryltrifluoroborates: Mild and efficient access to biaryls and terphenyls

Abstract A mild and efficient protocol has been developed for the Suzuki–Miyaura reaction of aryl fluorosulfates and potassium aryltrifluoroborates at room temperature. A series of biaryls can be prepared with excellent yields in this system and an aerobic atmosphere demonstrates a positive effect on the reactivity of the cross-coupling reactions. Additionally, this method can be extended to one-pot double Suzuki–Miyaura reactions, allowing the synthesis of various unsymmetrical terphenyls in moderate to good yields.